Figure 2.

LZ-3 improves behavioral and cognitive functions in rats on post-stroke.

(A–C) The neurological deficit score was evaluated from day 1 to day 8. (D–F) Escape latency in the Morris water maze navigation test. The Morris water maze test was performed from day 21 to day 26. (G and H) Time spent in the target quadrant and the number of platform crossings in the Morris water maze spatial probe test. Both values were determined for a 60-second period for each rat. Data are expressed as mean ± SD (n = 8). ##P < 0.01, vs. sham group; *P < 0.05, vs. model group. The neurological deficit scores were analyzed by non-parametric Kruskal-Wallis rank sum test, and the Morris water maze test results were analyzed by one-way analysis of variance followed by Tukey’s post hoc test. MCAO: Middle cerebral artery occlusion; Mod: model group.