Table 4.
Overview of bilateral areas of cluster-level significant effects of cortical thickness reduction in NMOSD-ON compared to non-NMOSD-ON
| Overlay of atlas region | Hemisphere | Cluster size | Peak MNI coordinates (mm) | FDR-corrected P-value | ||
|---|---|---|---|---|---|---|
|
| ||||||
| x | y | z | ||||
| 38% superiorparietal | L | 757 | –3 | –78 | 21 | < 0.001 |
| 29% cuneus | ||||||
| 20% pericalcarine | ||||||
| 6% lateraloccipical | ||||||
| 5% precuneus | ||||||
| 58% cuneus | R | 443 | 5 | –77 | 19 | 0.012 |
| 24% superiorparietal | ||||||
| 15% pericalcarine | ||||||
| 3% lateraloccipical | ||||||
Atlas labeling was conducted according to the Desikan-Killiany atlas. FDR: False discovery rate; L: left; NMOSD: neuromyelitis optica spectrum disorder; NMOSD-ON: NMOSD patients who experienced at least one clinical episode of optic neuritis; non-NMOSD-ON: NMOSD patients without clinical episodes of optic neuritis; R: right.