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. 2023 Mar 15;18(11):2474–2481. doi: 10.4103/1673-5374.371377

Figure 7.

Figure 7

Liproxstatin-1 improves functional recovery after SCI.

(A) Timeline of the functional evaluation after Lip-1 administration in T10 contusive SCI in rats. 7 dpi: 7 days post-injury. (B) Basso, Beattie and Bresnahan (BBB) scores of rats at different time points after injury (n = 12). (C) BBB scores of rats in each group at 8 weeks post-injury (n = 12). (D) Gait analysis of rats in different groups at 8 weeks after injury. Right front paw (blue), right hind paw (purple), left front paw (yellow), left hind paw (green). (E) Representative waveform of motor evoked potentials (MEP) at 8 weeks after injury. (F, G) Quantification of the latency and amplitude of the MEP (n = 12). (H) Representative waveform of somatosensory evoked potentials (SEP) at 8 weeks after injury. (I, J) Quantification of the latency and amplitude of the SEP (n = 12). Two-way analysis of variance followed by Tukey’s post hoc test for B; one-way analysis of variance followed by Tukey’s post hoc test for C, F, G, I, and J. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001. HE: Hematoxylin and eosin; Lip-1: liproxstatin-1; SCI: spinal cord injury; w: week.