Table 2.
The top 10 altered genes at the 3rd, 7th and 14th days after spared nerve injury (SNI)
| Group | Gene name | Description | Fold change | Regulation | P-value |
|---|---|---|---|---|---|
| SNI Day 3 | Gm26920 | Predicted gene, 26920 | –5.85 | Down | 1.00E-10 |
| Gm42878 | Predicted gene 42878 | –5.4 | Down | 0.0011 | |
| Ccl7 | Chemokine (C-C motif) ligand 7 | 5.17 | Up | 7.00E-11 | |
| Rps12l1 | Ribosomal protein S12-like 1 | 5.02 | Up | 1.00E-05 | |
| Sprr1a | Small proline-rich protein 1A | 4.41 | Up | 4.00E-13 | |
| Ppp1r3g | Protein phosphatase 1, regulatory subunit 3G | 4.2 | Up | 2.00E-12 | |
| Cyp2f2 | Cytochrome P450, family 2, subfamily f, polypeptide 2 | 4.07 | Up | 0.0003 | |
| Snhg4 | Small nucleolar RNA host gene 4 | 4.04 | Up | 0.0002 | |
| Atf3 | Activating transcription factor 3 | 3.89 | Up | 6.00E-28 | |
| Gm5763 | Predicted pseudogene 5763 | 3.11 | Up | 9.00E-05 | |
| SNI Day 7 | Serpina1e | Serine (or cysteine) peptidase inhibitor, clade A, member 1E | –7.75 | Down | 8.00E-06 |
| Gm42893 | Predicted gene 42893 | –6.35 | Down | 9.00E-14 | |
| Sprr1a | Small proline-rich protein 1A | 5.53 | Up | 2.00E-19 | |
| Fabp1 | Fatty acid binding protein 1, liver | –5.27 | Down | 0.0007 | |
| Ccl7 | Chemokine (C-C motif) ligand 7 | 5.21 | Up | 4.00E-10 | |
| Serpina3k | Serine (or cysteine) peptidase inhibitor, clade A, member 3K | –4.79 | Down | 1.00E-06 | |
| Apob | Apolipoprotein B | –4.56 | Down | 0.0073 | |
| Atf3 | Activating transcription factor 3 | 4.37 | Up | 4.00E-30 | |
| Serpina1a | Serine (or cysteine) peptidase inhibitor, clade A, member 1A | –4.32 | Down | 0.0045 | |
| Gm24270 | Predicted gene, 24270 | –4.16 | Down | 0.0025 | |
| SNI Day 14 | Fabp1 | Fatty acid binding protein 1, liver | –6.99 | Down | 1.00E-05 |
| Serpina1e | Serine (or cysteine) peptidase inhibitor, clade A, member 1E | –6.43 | Down | 8.00E-05 | |
| Sprr1a | Small proline-rich protein 1A | 5.64 | Up | 1.00E-22 | |
| Serpina3k | Serine (or cysteine) peptidase inhibitor, clade A, member 3K | –5.49 | Down | 0.0001 | |
| Apoa5 | Apolipoprotein A-V | –5.32 | Down | 0.0019 | |
| Serpina1d | Serine (or cysteine) peptidase inhibitor, clade A, member 1D | –5.27 | Down | 6.00E-05 | |
| Pigr | Polymeric immunoglobulin receptor | –4.69 | Down | 0.0018 | |
| Pzp | PZP, alpha-2-macroglobulin like | –4.57 | Down | 0.0004 | |
| Fga | Fibrinogen alpha chai | –4.53 | Down | 0.0103 | |
| Cyp2a5 | Cytochrome P450, family 2, subfamily a, polypeptide 5 | –4.43 | Down | 0.0015 |