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. 2023 Mar 15;18(11):2436–2442. doi: 10.4103/1673-5374.371368

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Copyright: © Neural Regeneration Research

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Increased Vav1 expression in the ischemic penumbra of MCAO/R rats.

(A) Vav1 mRNA expression in MCAO/R rats according to the GEO database GSE163614. (B) Vav1 mRNA expression (normalized to the sham group) in the ischemic penumbra of MCAO/R rats. (C) Normalized Vav1 protein expression in the ischemic penumbra of MCAO/R rats. (D) Cerebral infarction area expressed as a percentage of total brain area, as determined by TTC staining. Data are expressed as the mean ± SD (n = 6), and were analyzed by unpaired t-test. The experiments were repeated three times. GEO: Gene expression omnibus; MCAO/R: middle cerebral artery occlusion/reperfusion; TTC staining: triphenyltetrazolium chloride staining; Vav1: Vav guanine nucleotide exchange factor 1.