TABLE 7.
Serum liver function test of hyperlipidemic volunteers at baseline, day 30, and day 60 during phase 2 (mean ± SD).
| Control | 250 mg OPP | ||
|---|---|---|---|
| Total protein | |||
| Day 1 | 72.24 ± 3.74 | 70.92 ± 3.03 | |
| Day 30 | 72.24 ± 3.60 | 72.08 ± 4.55 | |
| Day 60 | 71.96 ± 4.10 | 72.36 ± 4.23 | |
| Albumin | |||
| Day 1 | 44.88 ± 2.01 | 44.76 ± 1.94 | |
| Day 30 | 44.84 ± 1.68 | 45.04 ± 2.75 | |
| Day 60 | 44.84 ± 1.80 | 45.80 ± 2.38 | |
| Globulin | |||
| Day 1 | 27.36 ± 3.08 | 26.16 ± 2.62 | |
| Day 30 | 27.40 ± 3.45 | 27.04 ± 3.23 | |
| Day 60 | 27.12 ± 3.35 | 26.56 ± 3.06 | |
| ALP (IU/L) | |||
| Day 1 | 67.48 ± 15.38 | 75.24 ± 22.65 | |
| Day 30 | 65.16 ± 15.70 | 75.48 ± 19.87 | |
| Day 60 | 65.88 ± 15.35 | 76.72 ± 20.28 | |
| AST (IU/L) | |||
| Day 1 | 20.80 ± 7.54 | 22.32 ± 5.84 | |
| Day 30 | 22.88 ± 11.65 | 23.12 ± 6.30 | |
| Day 60 | 21.20 ± 8.76 | 23.16 ± 4.37 | |
| ALT (IU/L) | |||
| Day 1 | 20.92 ± 15.49 | 21.56 ± 11.15 | |
| Day 30 | 25.40 ± 18.83a | 25.88 ± 17.21 | |
| Day 60 | 24.16 ± 18.90a | 25.16 ± 14.32 | |
| GGT (IU/L) | |||
| Day 1 | 22.40 ± 11.73 | 23.84 ± 16.01 | |
| Day 30 | 25.16 ± 10.55 | 28.72 ± 22.14a | |
| Day 60 | 22.76 ± 10.23c | 26.12 ± 17.48 | |
Abbreviation: ALP, alkaline phosphatase; AST, aspartate transaminase; ALT, alanine transaminase; GGT, gamma-glutamyl transferase.
aSignificantly different compared to day 1 within the group (p < 0.05).
bSignificantly different compared to day 1 within the group (p < 0.001).
cSignificantly different compared to day 30 within the group (p < 0.05).