Skip to main content
. 2023 Jul 20;24:171. doi: 10.1186/s13059-023-03012-w

Fig. 4.

Fig. 4

Allele-specific editing reflected in the GM12878 long-read RNA-seq data. a Mutual information of known editing sites (REDIportal). Six sites with high mutual information were randomly chosen for experimental testing (arrows). b Summary of experimental validation results. Four out of 6 sites were confirmed as RNA editing sites. cf Sanger sequencing traces for 4 confirmed editing sites. d IGV plot for an example allele-specific editing event: between the RNA editing site chr1:9102175 (red rectangle) and three heterozygous SNPs (blue rectangle). Note that the gene is on the − strand