Table 3.
Receiver operating characteristic analysis for the prediction of MACEs by IR indices
| Variables | AUC (95% CI) | Cut‐off value | Specificity | Sensitivity | P for comparison |
|---|---|---|---|---|---|
| All participants | |||||
| METS‐IR | 0.596 (0.585–0.607) | 28.529 | 0.546 | 0.627 | – |
| HOMA‐IR | 0.599 (0.588–0.611) | 1.128 | 0.503 | 0.673 | 0.835 |
| TyG | 0.600 (0.589–0.612) | 8.392 | 0.461 | 0.725 | 0.744 |
| TyG‐BMI | 0.571 (0.559–0.582) | 170.474 | 0.592 | 0.574 | 0.000 |
| TyG‐WHtR | 0.561 (0.550–0.573) | 4.236 | 0.490 | 0.667 | 0.014 |
| TyG‐WC | 0.547 (0.536–0.559) | 670.524 | 0.487 | 0.648 | 0.001 |
| Without diabetes | |||||
| METS‐IR | 0.588 (0.576–0.599) | 28.492 | 0.462 | 0.730 | – |
| HOMA‐IR | 0.597 (0.586–0.609) | 1.116 | 0.458 | 0.765 | 0.567 |
| TyG | 0.594 (0.582–0.605) | 8.219 | 0.483 | 0.728 | 0.678 |
| TyG‐BMI | 0.564 (0.552–0.576) | 168.304 | 0.657 | 0.514 | 0.000 |
| TyG‐WHtR | 0.553 (0.541–0.565) | 4.089 | 0.486 | 0.662 | 0.030 |
| TyG‐WC | 0.538 (0.526–0.550) | 690.675 | 0.619 | 0.521 | 0.004 |
| Diabetes | |||||
| METS‐IR | 0.635 (0.595–0.674) | 39.361 | 0.615 | 0.634 | – |
| HOMA‐IR | 0.598 (0.558–0.637) | 2.345 | 0.692 | 0.537 | 0.021 |
| TyG | 0.593 (0.553–0.633) | 9.163 | 0.582 | 0.629 | 0.019 |
| TyG‐BMI | 0.567 (0.526–0.607) | 198.591 | 0.453 | 0.734 | 0.000 |
| TyG‐WHtR | 0.587 (0.546–0.626) | 5.402 | 0.726 | 0.473 | 0.013 |
| TyG‐WC | 0.559 (0.519–0.599) | 739.920 | 0.459 | 0.692 | 0.018 |
P for significance of comparison between METS‐IR and other IR indices. Values in bold indicate statistical significance (P value < 0.05). AUC, area under the curve; CI, confidential interval; MACEs, major adverse cardiovascular events; METS‐IR, metabolic score for insulin resistance.