Table 4.
Discrimination of each predictive model for MACEs using the C‐index, continuous NRI, and IDI
| C‐index (95% CI) | P Value | Continuous NRI (95% CI) | P Value | IDI (95% CI) | P Value | |
|---|---|---|---|---|---|---|
| All participants | ||||||
| Established risk factors | 0.707 (0.678–0.737) | Reference | Reference | |||
| Established risk factors + METS‐IR | 0.716 (0.686–0.746) | <0.001 | 0.173 (0.063–0.292) | 0.003 | 0.010 (0.006–0.014) | <0.001 |
| Without diabetes | ||||||
| Established risk factors | 0.698 (0.667–0.729) | Reference | Reference | |||
| Established risk factors + METS‐IR | 0.707 (0.675–0.738) | <0.001 | 0.155 (0.032–0.284) | 0.014 | 0.008 (0.004–0.011) | <0.001 |
| Diabetes | ||||||
| Established risk factors | 0.801 (0.725–0.876) | Reference | Reference | |||
| Established risk factors + METS‐IR | 0.817 (0.742–0.891) | <0.001 | 0.427 (0.037–0.833) | 0.043 | 0.023 (0.002–0.044) | 0.028 |
Established risk factors included age, sex, HbA1c, 2 h PG, fasting insulin, LDL, TC, WHR, hypertension, hyperlipidemia, current smoking, and current drinking. Values in bold indicate statistical significance (P value < 0.05). NRI, net reclassification index; IDI, integrated discrimination improvement; MACEs, major adverse cardiovascular event; METS‐IR, metabolic score for insulin resistance.