Table 3.
Baseline characteristics of the third cohort by the predicted genotypes.
| Overall |
|||
|---|---|---|---|
| Predicted G- (n = 51) |
Predicted G+ (n = 25) |
p-value | |
| Demography | |||
| Age | 56.02 ± 16.24 | 53.60 ± 7.16 | 0.48 |
| Male | 35 (68.63) | 17 (68.00) | 0.96 |
| Medical history | |||
| Hypertension | 26 (50.98) | 7 (28.00) | 0.06 |
| Family history of HCM | 2 (3.92) | 9 (36.00) | <0.01 |
| Family history of SCD | 6 (11.76) | 7 (28.00) | 0.08 |
| Syncope | 7 (13.73) | 6 (24.00) | 0.26 |
| Clinical | |||
| NYHA | 0.88 | ||
| Class I | 19 (37.25) | 9 (36.00) | |
| Class II | 22 (43.14) | 12 (48.00) | |
| Class III | 9 (17.65) | 3 (12.00) | |
| Class IV | 1 (1.96) | 1 (4.00) | |
| Non-sustained VT | 7 (13.73) | 11 (44.00) | <0.01 |
| Echocardiography | |||
| LVEF | 70.29 ± 6.70 | 69.83 ± 7.73 | 0.79 |
| Maximal left ventricular wall thickness | 20.85 ± 4.17 | 21.95 ± 4.16 | 0.30 |
| Left atrial dimension | 42.72 ± 6.83 | 42.71 ± 7.15 | 0.99 |
| LVOT gradient | 10.24 (38.43) | 9.00 (20.68) | 0.82 |
G–: genotype negativity; G+: genotype positivity; HCM: hypertrophic cardiomyopathy; SCD: sudden cardiac death; LVEF: left ventricular ejection fraction; NYHA: New York Heart Association; LVOT: left ventricular outflow tract; VT: ventricular tachycardia. LVOT: gradient was presented as median (interquartile range).