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. 2023 Jun 2;44(28):2595–2605. doi: 10.1093/eurheartj/ehad328

Table 1.

Prevalence of elevated hs-troponina, overall and according to characteristics of US adults aged 18 or older without a history of CVD, NHANES 1999–2004

Elevated (>99 percentile) hs-troponin T by Rochea Elevated (>99 percentile) hs-troponin I by Abbotta Elevated (>99 percentile) hs-troponin I by Siemensa Elevated (>99 percentile) hs-troponin I by Orthoa
Total, % 3.11 0.60 0.93 0.75
Gender, %
 Male 2.54 0.52 1.02 0.66
 Female 3.62 0.67 0.85 0.82
Age categories, %
 18–39 years 0.33 0.36 0.41 0.32
 40–59 years 1.74 0.38 0.70 0.48
 60 years or older 12.6 1.64 2.64 2.32
Race/ethnicity, %
 NH White 3.34 0.55 0.81 0.74
 NH Black 4.35 1.48 1.71 1.50
 Mexican–American 1.19 0.43 0.88 0.22
 Other/other Hispanic 1.66 0.16 1.00 0.41
Hypertension, %
 No 1.51 0.37 0.60 0.44
 Yes 7.70 1.21 1.82 1.57
Hypercholesterolemia, %
 No 2.49 0.51 0.79 0.65
 Yes 5.15 0.89 1.40 1.05
eGFR, mL/min/1.73 m2, %
 >90 1.84 0.34 0.57 0.36
 60–90 21.3 0.96 2.36 1.28
 <60 65.3 7.86 5.35 11.4
Smoking status, %
 Current 2.08 0.49 0.62 0.43
 Former 4.75 0.77 1.38 1.37
 Never 2.84 0.57 0.87 0.61
Family history of CVD, %
 No 3.32 0.64 1.02 0.79
 Yes 1.83 0.36 0.36 0.50
Diabetes mellitus, %
 No 2.73 0.55 0.88 0.74
 Yes 10.1 1.55 1.97 0.91
BMI, kg/m2, %
 <25 3.36 0.63 0.98 0.72
 25–30 2.87 0.53 0.99 0.85
 >30 3.10 0.64 0.81 0.65

BMI, body mass index; CVD, cardiovascular disease; eGFR, estimated glomerular filtration ratio using the creatinine cystatin equation; HDL, high-density lipoprotein; NH, non-Hispanic; SBP, systolic blood pressure; URL, upper reference limit.

Values above the manufacturer-designated assay- and sex-specific 99th percentile URL myocardial injury threshold were defined as elevated; troponin T 14(f)/22(m) ng/L; troponin I, Abbott 17(f)/35(m) ng/L; troponin I, Siemens 39.6(f)/58(m) ng/L; troponin I, Ortho 9(f) 12(m) ng/L.