Fig. 7.

A) First two steps represents the shematic diagram of the synthesis of the monoclonal anti-tau aggregate antibody conjugated gold nanoparticles wherease the last step represents the color change of the anti-tau aggregate antibody conjugated gold nanoparticles when they bind to the tau protein aggregate. B) TEM image of the anti-tau antibody conjugated gold nanoparticles C) TEM image of the anti-tau antibody conjugated gold nanoparticle after the binding with tau protein. Figure was reprinted from Ref. [136] under the persmison of the publisher.