Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Jul 7;14:1197212. doi: 10.3389/fneur.2023.1197212

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2023 Macaron, Larochelle, Arbour, Galmard, Girard, Prat and Duquette.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Peripheral immune system and CNS alterations associated with aging (A,B created with BioRender.com). (A–C) Summary of the physiological functions and characteristics that are altered with age. (A) Immunosenescence in the periphery. Alterations reported as enhanced in patients with MS compared with age-matched controls are identified in bold. (B) Physiological mechanisms altered in the aging CNS and potentially relevant to MS pathobiology. (C) Physiological functions decreasing (blue triangle) or increasing (orange triangle) with age and associated with inflammaging (in bold: MS-specific changes).