Table 4. Univariate logistic analysis of clinical pregnancy rates for infertile patients from two embryo groups.
Variables | Cleavage group | Blastocyst group | |||||
---|---|---|---|---|---|---|---|
OR | 95% CI | P- value | OR | 95% CI | P- value | ||
Age (years) | 0.92 | 0.91–0.94 | <0.001 | 0.96 | 0.93–0.98 | 0.016 | |
BMI (kg/m2) | 0.99 | 0.96–1.02 | 0.715 | 0.98 | 0.94–1.03 | 0.499 | |
Duration of infertility (years) | 0.97 | 0.94–0.99 | 0.024 | 0.95 | 0.90–1.01 | 0.142 | |
Fertilization method (IVF vs. ICSI) |
1.02 | 0.72–1.33 | 0.774 | 1.14 | 0.94–1.71 | 0.121 | |
Previous cycle attempts | |||||||
1-2 vs. 0 | 0.62 | 0.50–0.77 | <0.001 | 1.02 | 0.67–1.56 | 0.932 | |
≥3 vs. 0 | 0.12 | 0.06–0.23 | <0.001 | 0.59 | 0.19–1.83 | 0.387 | |
Sterility classification (Secondary vs. Primary) |
0.83 | 0.70–0.98 | 0.039 | 1.16 | 0.86–1.56 | 0.325 | |
Basal FSH (mIU/ml) | 0.92 | 0.89–0.95 | <0.001 | 0.98 | 0.91–1.05 | 0.580 | |
Basal LH (mIU/ml) | 1.02 | 0.97–1.06 | 0.327 | 0.94 | 0.87–1.01 | 0.120 | |
Basal E2 (pg/ml) | 0.99 | 0.99–1.01 | 0.232 | 0.99 | 0.99–1.01 | 0.887 | |
hCG day FSH (mIU/ml) | 0.95 | 0.94–0.97 | <0.001 | 0.96 | 0.93–1.01 | 0.031 | |
hCG day LH (mIU/ml) | 0.98 | 0.94–1.01 | 0.179 | 1.03 | 0.94–1.11 | 0.527 | |
hCG day E2 (pg/ml) | |||||||
Set 1 | Reference | Reference | |||||
Set 2 | 1.54 | 1.27–1.89 | <0.001 | 0.75 | 0.52–1.18 | 0.124 | |
Set 3 | 1.64 | 1.28–2.10 | <0.001 | 0.97 | 0.66–1.43 | 0.869 | |
Set 4 | 1.23 | 0.83–1.84 | 0.303 | 0.52 | 0.29–0.94 | 0.0308 | |
hCG day P (ng/ml) | 0.95 | 0.73–1.24 | 0.708 | 0.50 | 0.31–0.80 | 0.004 | |
Endometrial thickness (mm) | 1.14 | 1.09–1.18 | <0.001 | 1.010 | 0.94–1.09 | 0.636 | |
No. of retrieved oocytes | 1.05 | 1.03–1.07 | <0.001 | 0.98 | 0.95–1.02 | 0.457 | |
No. of inviable embryos | 1.08 | 1.04–1.13 | 0.003 | 1.03 | 0.93–1.06 | 0.968 | |
No. of embryos transferred (2 vs. 1) |
2.30 | 1.80–2.93 | <0.001 | 1.76 | 1.05–2.93 | 0.031 |
Notes.
Abbreviations
- E2
- estradiol
- BMI
- body mass index
- IVF
- in-vitro fertilization
- ICSI
- intracytoplasmic sperm injection
- FSH
- follicle stimulating hormone
- LH
- luteinizing hormone
- hCG
- human chorionic gonadotropin
- P
- progesterone
- OR
- odds ratio
- CI
- confidence interval