Figure 8.

6-10B cells were co-cultured with exosomes derived from silenced miR-18a-5pin CNE-2 cells. The transplanted models were established by subcutaneous injection of 6-10B cells into mice. The pulmonary metastasis models were established by injection of 6-10B cells into tail veins of mice. a. Representative image of transplanted tumors. b. Measurement of volume and weight of the transplanted tumors. c. The number of pulmonary metastases was determined by H&E staining. d. The expression levels of miR-18a-5p and BTG3 were detected using RT-qPCR. e. The expression levels of BTG3, E-cadherin, and vimentin in the transplanted tumors were determined by immunohistochemistry.