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. 2023 Jun 10;9(6):e17060. doi: 10.1016/j.heliyon.2023.e17060

Table 2.

GHRP-2, growth hormone-releasing peptide-2; GH, growth hormone; CRH, corticotropin-releasing hormone; ACTH, adrenocorticotropic hormone; TRH, thyrotropin-releasing hormone; TSH, thyroid-stimulating hormone; PRL, prolactin; LHRH, luteinizing hormone-releasing hormone; LH, luteinizing hormone; FSH, follicle-stimulating hormone. Percentage in parentheses represents the proportion of cases for each group. *Statistically significant at p < 0.05.

Early elderly Late elderly p Value
GHRP-2 test, cases
 GH preoperative normal 28 (40.0%) 7 (24.1%) 0.204
 GH preoperative deficiency 42 (60.0%) 22 (75.9%)
 GH postoperative normal 31 (44.3%) 9 (31.0%) 0.318
 GH postoperative deficiency 39 (55.7%) 20 (69.0%)
CRH test, cases
 ACTH preoperative normal 35 (50.0%) 19 (65.5%) 0.234
 ACTH preoperative deficiency 35 (50.0%) 10 (34.5%)
 ACTH postoperative normal 58 (82.9%) 26 (89.7%) 0.543
 ACTH postoperative deficiency 12 (17.1%) 3 (10.3%)
 Cortisol preoperative normal 36 (51.4%) 8 (27.6%) 0.051
 Cortisol preoperative deficiency 34 (48.6%) 21 (72.4%)
 Cortisol postoperative normal 32 (45.7%) 8 (27.6%) 0.148
 Cortisol postoperative deficiency 38 (54.3%) 21 (72.4%)
TRH test, cases
 TSH preoperative normal 67 (95.7%) 23 (79.3%) 0.017*
 TSH preoperative deficiency 3 (4.3%) 6 (20.7%)
 TSH postoperative normal 47 (67.1%) 13 (44.8%) 0.045*
 TSH postoperative deficiency 23 (32.9%) 16 (55.2%)
 PRL preoperative normal 46 (65.7%) 18 (62.1%) 0.909
 PRL preoperative deficiency 24 (34.3%) 11 (37.9%)
 PRL postoperative normal 57 (81.4%) 23 (79.3%) 1.000
 PRL postoperative deficiency 13 (18.6%) 6 (20.7%)
LHRH test, cases
 LH preoperative normal 17 (24.3%) 6 (20.7%) 0.901
 LH preoperative deficiency 53 (75.7%) 23 (79.3%)
 LH postoperative normal 17 (24.3%) 10 (34.5%) 0.430
 LH postoperative deficiency 53 (75.7%) 19 (65.5%)
 FSH preoperative normal 31 (44.3%) 14 (48.3%) 0.888
 FSH preoperative deficiency 39 (55.7%) 15 (51.7%)
 FSH postoperative normal 26 (37.1%) 12 (41.4%) 0.867
 FSH postoperative deficiency 44 (62.9%) 17 (58.6%)