Fig. 4.
Representative (A) Mononucleated cell without MN, (B) Mononucleated cell with one MN, (C) Mononucleated cell with two MN, (D) Binucleated cell without MN, (E) Binucleated cell with one MN, and (F) Binucleated cell with one MN and a nucleoplasmic-bridge, (G and H) Tri and tetra-nucleated cells without MN. Only binucleated cells (without nucleoplasmic-bridge) were taken into account for construction of the dose response curve. Mono, tri and tetra nucleated-cells were not accounted in dose-response curve generation.