Table 4.
Yield and distribution of micronuclei, following ex vivo irradiation of 0–5 Gy (6 MeV, X-ray). All sets of data were over dispersed and were fitted by a linear quadratic model (Y C + αD + βD2) using Dose Estimate software, version 5.2. D0, D1, D2, D3, D4, D5 and D6, represents binucleated cells with 0, 1, 2, 3, 4, 5 and 6 micronuclei, respectively.
Dose (Gy) | Cells scored | MN (No) | Distribution of Micronuclei (MN) |
Yield (Y) | Relative Variance σ2/Y |
Dispersion Index (u) | Poisson Distribution | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D0 | D1 | D2 | D3 | D4 | D5 | D6 | |||||||
0 | 5000 | 36 | 4966 | 32 | 2 | 0 | 0 | 0 | 0 | 0.007 | 0.02 | 5.28 | OD |
0.1 | 5000 | 72 | 4934 | 60 | 6 | 0 | 0 | 0 | 0 | 0.014 | 0.02 | 7.68 | OD |
0.25 | 5000 | 92 | 4918 | 72 | 10 | 0 | 0 | 0 | 0 | 0.018 | 0.02 | 10 | OD |
0.5 | 5000 | 174 | 4844 | 139 | 16 | 1 | 0 | 0 | 0 | 0.035 | 0.02 | 9.22 | OD |
0.75 | 5000 | 248 | 4777 | 201 | 19 | 3 | 0 | 0 | 0 | 0.05 | 0.02 | 8.84 | OD |
1 | 5000 | 400 | 4650 | 307 | 38 | 3 | 2 | 0 | 0 | 0.08 | 0.02 | 10.8 | OD |
2 | 5000 | 855 | 4275 | 622 | 79 | 21 | 3 | 0 | 0 | 0.171 | 0.02 | 10.2 | OD |
3 | 5000 | 1502 | 3809 | 933 | 213 | 38 | 6 | 1 | 0 | 0.3 | 0.02 | 9.83 | OD |
4 | 5000 | 2500 | 3146 | 1378 | 352 | 88 | 28 | 6 | 2 | 0.5 | 0.02 | 9.97 | OD |
5 | 5000 | 3477 | 2470 | 1881 | 424 | 168 | 44 | 10 | 3 | 0.695 | 0.02 | 3.69 | OD |