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FAs downregulate the expressions of COX-2/PGE2/EP4 related proteins. (A) The expression of PGE2 in serum (p < 0.001, one-way ANOVA, n = 30), (B) COX-2 and EP4 were assayed by western blotting, β-Actin served as a loading control, and the expressions of (C) COX-2 and (D) EP4 (p < 0.001, one-way ANOVA, n = 4 independent experiments) in tumor tissue. Means not sharing any lowercase letters are significantly different by the SNK test at the 5% level of significance.
