Fig. 6.
JuB inhibited angiogenesis via the VEGFR2 signaling pathways. (A) JuB suppressed the activation of VEGFR2 and its downstream signaling mediators (FAK, PLCγ1, Akt, and Src) in HUVECs. (B) Schematic diagram of JuB-mediated antiangiogenic signaling pathway. All values were shown as mean ± s.d. *p < 0.05, **p < 0.01, ***p < 0.001.