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LASSO-Cox regression analysis develops a 4-driver genes signature in the TCGA cohort. (A)Univariate Cox analysis identified prognosis-related 7 driver genes. (B)Determination of the number of factors by LASSO analysis. (C)The distribution of risk scores and survival status. (D)Heatmap of 4-driver gene expression. (E)K–M survival analysis of the OS between the risk groups. (F)The time-dependent ROC curves of the risk signature predict OS of 1-, 3-, and 5- years.
