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. 2023 Jul 7;11:1212230. doi: 10.3389/fbioe.2023.1212230

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Copyright © 2023 Roe, Do, Turner, Jevitt, Chlebicz, White, Oomens, Rankin, Kovats and Gappa-Fahlenkamp.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Whole model dynamic qPCR array shows increased expression of genes associated with macrophage activation, IFN signaling, viral sensing and antiviral activity, and PRR signaling after challenge with RSV. (A) Genes associated with macrophage activation pathways. (B) Genes associated with IFN signaling pathways. (C) Genes associated with viral sensing and antiviral activity. (D) Genes associated with PRR signaling. IPA used to determine pathways of gene association. * represents p < 0.05, ** represents p < 0.01, *** represents p < 0.001. n = 3 myeloid donors. Unpaired two-tailed t-test.