Table 3.
Concordance between the qualitative CSF-TRUST-10 and CSF-TRUST-17 tests and the CSF-VDRL.
| CSF-VDRL | P for χ2 | Positive predictive value | Negative predictive value | Agreement | κ | P for κ | ||
|---|---|---|---|---|---|---|---|---|
| Positive | Negative | |||||||
| CSF-TRUST-10 | ||||||||
| The whole cohort (n = 152)a | 0.500 | 100.0% | 97.9% | 98.7% | 0.972 | <0.001 | ||
| Positive | 57 | 0 | ||||||
| Negative | 2 | 93 | ||||||
| Subgroups by sex | ||||||||
| Male (n = 86) | >0.999 | 100.0% | 100.0% | 100.0% | 1.0 | <0.001 | ||
| Positive | 39 | 0 | ||||||
| Negative | 0 | 47 | ||||||
| Female (n = 66) | 0.500 | 100.0% | 95.8% | 97.0% | 0.926 | <0.001 | ||
| Positive | 18 | 0 | ||||||
| Negative | 2 | 46 | ||||||
| Subgroups by age | ||||||||
| <60 (n = 127) | 0.500 | 100.0% | 97.6% | 98.4% | 0.965 | <0.001 | ||
| Positive | 43 | 0 | ||||||
| Negative | 2 | 82 | ||||||
| ≥60 (n = 25) | >0.999 | 100.0% | 100.0% | 100.0% | 1.0 | <0.001 | ||
| Positive | 14 | 0 | ||||||
| Negative | 0 | 11 | ||||||
| CSF-TRUST-17 | ||||||||
| The whole cohort (n = 210) | 0.125 | 100.0% | 96.8% | 98.1% | 0.961 | <0.001 | ||
| Positive | 85 | 0 | ||||||
| Negative | 4 | 121 | ||||||
| Subgroups by sex | ||||||||
| Male (n = 129) | 0.500 | 100.0% | 97.0% | 98.4% | 0.969 | <0.001 | ||
| Positive | 63 | 0 | ||||||
| Negative | 2 | 64 | ||||||
| Female (n = 81) | 0.500 | 100.0% | 96.6% | 97.5% | 0.939 | <0.001 | ||
| Positive | 22 | 0 | ||||||
| Negative | 2 | 57 | ||||||
| Subgroups by age | ||||||||
| <60 (n = 176) | 0.250 | 100.0% | 97.3% | 98.3% | 0.964 | <0.001 | ||
| Positive | 65 | 0 | ||||||
| Negative | 3 | 108 | ||||||
| ≥60 (n = 34) | >0.999 | 100.0% | 92.9% | 97.1% | 0.939 | <0.001 | ||
| Positive | 20 | 0 | ||||||
| Negative | 1 | 13 | ||||||
Abbreviations: CSF, cerebrospinal fluid; VDRL, venereal disease research laboratory; TRUST, toluidine red unheated serum test.
a
The results of the CSF-TRUST-10 test were missing for 58 participants.