Table 4.
Correlations between IL-23 and IL-27 values and the clinical characteristics of CIS and SPMS patients.
| Variables |
IL-23 (pg./ml) |
IL-27(pg./ml) |
|---|---|---|
| Correlation Coefficient ρ (p-value) | Correlation Coefficient ρ (p-value) | |
| CIS group (n = 6) | ||
| Age (years) | −0.35 (0.499) | 0.29 (0.577) |
| Age at disease onset (years) | 0.06 (0.913) | 0.09 (0.869) |
| Duration of disease (years) | −0.20 (0.699) | 0.06 (0.913) |
| EDDS (points) | 0.78 (0.069) | −0.78 (0.069) |
| Duration of Disease-modifying treatment (months) | −0.54 (0.297) | 0.43 (0.419) |
| Number of relapses under treatment | NA | NA |
| SPMS group (n = 9) | ||
| Age (years) | −0.22 (0.581) | 0.75 (0.021*) |
| Age at disease onset (years) | −0.48 (0.192) | 0.34 (0.368) |
| Duration of disease (years) | 0.34 (0.366) | 0.06 (0.881) |
| EDDS (points) | −0.04 (0.729) | −0.08 (0.500) |
| Duration of Disease-modifying treatment (months) | 0.70 (0.037*) | −0.17 (0.653) |
| Number of relapses under treatment | −0.27 (0.478) | 0.14 (0.724) |
*significant result: p < 0.05; ρ = Spearman correlation coefficient; NA = not available (no CIS patients with relapses under treatment).