FIG. 3.
The family of soft-metal-ion-translocating P-type ATPases. This family is growing rapidly, so only representative ones are shown. GenBank accession numbers are given in parentheses. The dendograms were made using the CLUSTAL4 algorithm (22) with DNASIS software from Hitachi Software Engineering Co., Ltd. The calculated matching percentages are indicated at each branch point. Zn(II)/Pb(II)/Cd(II) pumps: ZntA, E. coli (P37617); ZntA, P. mirabilis (CAA04762); CadA, Bacillus firmus (AAA22858); CadA, pI258 (AAB59154); CadA, Tn5422 (L28104); CadA, H. pylori (AAA93043); ZiaA, Synechocystis sp. strain PCC 6803 (Q59998); P. aeruginosa reading frame (unfinished genome); Chlamydia pneumoniae reading frame (AAD19006); A. thaliana reading frame (CAB16773). Cu(I)/Ag(I) pumps: MNK, human Menkes disease-related protein (Q04656); WND, human Wilson disease-related protein (U03464); PacS, Archaeoglobus fulgidus (AE0010711); CopA, E. hirae copper uptake pump (P32113); CopA, E. coli (AAB02268); SilP, S. typhimurium Ag(I) pump (AAD11750); PacS, Synechocystis sp. strain PCC 6803 (P73241); CtaA, Synechococcus sp. strain PCC 7942 (P37385); CopA, H. pylori (AAB05475); CCC2, S. cerevisiae vacuolar copper pump (L363171); CopB E. hirae copper efflux pump (P05425).