Table 2.
Self-Reported CIA by Means of EORTC QLQ – Items Hair Loss
| Scalp Cooling Group (N=75) | Control Group (N=38) | Group-by-Time Interaction | |
|---|---|---|---|
| *EORTC Item Library – Have you lost any hair? | Mean (95% CI) | Mean (95% CI) | P=0.361 |
| Time point 1 (baseline) | 1.36 (1.13–1.59) | 1.50 (1.17–1.82) | |
| Time point 2 (mid chemotherapy) | 3.28 (3.05–3.50) | 3.60 (3.28–3.93) | |
| Time point 3 (last CT cycle) | 3.08 (2.85–3.30) | 3.40 (3.04–3.76) | |
| Time point 4 (3 months after treatment completion) | 1.66 (1.40–1.90) | 1.56 (1.18–1.93) | |
| Time point 5 (6–9 months after CT completion) | 1.24 (0.99–1.48) | 1.07 (0.70–1.44) | |
| *EORTC QLQ – Were you upset by the loss of your hair? | P=0.073 | ||
| Time point 1 (baseline) | 1.55 (1.25–1.86) | 1.97 (1.55–2.40) | |
| Time point 2 (mid chemotherapy) | 2.76 (2.5–3.00) | 2.56 (2.22–2.93) | |
| Time point 3 (last CT cycle) | 2.43 (2.18–2.68) | 2.33 (1.96–2.70) | |
| Time point 4 (3 months after treatment completion) | 1.93 (1.65–2.21) | 1.60 (1.18–2.00) | |
| Time point 5 (6–9 months after CT completion) | 1.76 (1.46–2.06) | 1.16 (0.72–1.60) | |
| *EORTC QLQ – Have you been upset by how the treatment has affected your hair? | P=0.108 | ||
| Time point 1 (baseline) | 1.45 (1.11–1.79) | 1.80 (1.36–2.24) | |
| Time point 2 (mid chemotherapy) | 2.53 (2.28–2.79) | 2.15 (1.79–2.51) | |
| Time point 3 (last CT cycle) | 2.25 (1.99–2.50) | 2.13 (1.75–2.50) | |
| Time point 4 (3 months after treatment completion) | 1.98 (1.70–2.26) | 1.70 (1.25–2.14) | |
| Time point 5 (6–9 months after CT completion) | 1.87 (1.58–2.15) | 1.44 (1.25–2.14) | |
| *EORTC QLQ – Have you had thin or lifeless hair as a result of your disease or treatment? | P=0.219 | ||
| Time point 1 (baseline) | 1.21 (0.85–1.57) | 1.53 (1.04–2.02) | |
| Time point 2 (mid chemotherapy) | 2.29 (2.01–2.57) | 2.25 (1.74–2.76) | |
| Time point 3 (last CT cycle) | 1.97 (1.67–2.26) | 2.42 (1.90–2.93) | |
| Time point 4 (3 months after treatment completion) | 1.86 (1.55–2.18) | 1.54 (0.99–2.08) | |
| Time point 5 (6–9 months after CT completion) | 1.61 (1.31–1.91) | 1.53 (1.04–2.02) |
Notes: P-values are reported for the group-by-time interaction, ie the group-difference in change over time. *© EORTC Quality of Life Group. All rights reserved.