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. Author manuscript; available in PMC: 2024 Jan 1.
Published in final edited form as: Tuberculosis (Edinb). 2022 Dec 27;138:102302. doi: 10.1016/j.tube.2022.102302

Figure 6. All prime/boost vaccine strategies provide prophylactic pulmonary protection against M. avium in beige mice.

Figure 6.

Beige mice were infected with M. avium 2-151 smt by aerosol route four weeks post final immunization. (A-C) Bacterial burden was assessed by colony forming unit (CFU) in lung (A), spleen (B), and liver (C) organ homogenates six weeks post challenge. CFU means were compared between each group using one-way ANOVA with Dunnett’s multiple comparisons test. Black line and error bars show mean ± SEM, dots represent individual mice, n = 6–7/group. Asterisks indicate statistical significance, where *p < 0.05, **p < 0.01, ***p < 0.001 and ****p < 0.0001.