Table 3.
General Characteristics of Subjects in the Training and Validation Datasets According to the Development of Metabolic Syndrome
| Variables | Training Dataset (2009 Group) | External Validation Dataset (2019 Group) | ||||
|---|---|---|---|---|---|---|
| Non-MetS | MetS | p-value | Non-MetS | MetS | p-value | |
| N=4501 (92.9) | N=346 (7.1) | N=3728 (86.2) | N=596 (13.8) | |||
| Gender | ||||||
| Male, n (%) | 2867 (63.70) | 298 (86.13) | <0.001 | 1918 (51.45) | 562 (94.30) | <0.001 |
| Female, n (%) | 1634 (36.30) | 48 (13.87) | <0.001 | 1810 (48.55) | 34 (5.70) | <0.001 |
| Age, (years) | 45.97 ± 13.74 | 54.73 ± 12.81 | <0.001 | 44.34 ± 13.22 | 46.47 ± 14.84 | 0.0003 |
| BMI (kg/m2) | 23.35 ± 2.87 | 27.39 ± 2.27 | <0.001 | 23.29 ± 1.82 | 27.05 ± 0.44 | <0.001 |
| SBP (mmHg) | 120.35 ± 21.05 | 141.13 ± 15.98 | <0.001 | 126.84 ± 13.07 | 167.96 ± 8.87 | <0.001 |
| DBP (mmHg) | 79.90 ± 10.46 | 93.34 ± 9.67 | <0.001 | 74.05 ± 9.27 | 92.52 ± 1.36 | <0.001 |
| FBG (mg/dL) | 94.87 ± 18.42 | 125.76 ± 36.77 | <0.001 | 87.65 ± 7.64 | 120.65 ± 8.46 | <0.001 |
| TG (mg/dL) | 134.46 ± 106.74 | 266.23 ± 246.29 | <0.001 | 123.18 ± 55.05 | 331.13 ± 34.20 | <0.001 |
| TC (mg/dL) | 176.11 ± 33.70 | 187.95 ± 37.55 | <0.001 | 167.96 ± 23.59 | 225.62 ± 5.18 | <0.001 |
| HDL-C (mg/dL) | 48.57 ± 12.28 | 38.51 ± 9.96 | <0.001 | 48.12 ± 10.25 | 74.58 ± 2.30 | <0.001 |
| LDL-C (mg/dL) | 95.49 ± 25.51 | 99.09 ± 26.48 | <0.001 | 93.19 ± 19.46 | 141.20 ± 4.52 | <0.001 |
| SUA (mg/dL) | 5.22 ± 1.33 | 6.19 ± 1.36 | <0.001 | 5.32 ± 1.17 | 7.90 ± 0.32 | <0.001 |
Notes: Continuous variables were represented as mean ± standard deviation and categorical data were represented as a number (percentage). P-values of normal-distribution date derived from Student’s t-test; and P-values of categorical data derived from chi-squared test.
Abbreviations: MetS, metabolic syndrome; BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; FBG, fasting blood glucose; TG, triglycerides; TC, total cholesterol; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; SUA, serum uric acid.