Table 4. Stratified analysis based on mode of inheritance for NAT2 SNP (rs1799930) across AML patients and healthy controls.
| Model | Genotype | Case n (%) | Control n (%) | OR (95% CI) | P-value | AIC | BIC |
|---|---|---|---|---|---|---|---|
| Codominant | G/G | 20 (69) | 95 (43.6) | 1 | 0.018 | 176.7 | 187.2 |
| G/A | 6 (20.7) | 102 (46.8) | 3.58 (1.38–9.29) | ||||
| A/A | 3 (10.3) | 21 (9.6) | 1.47 (0.40–5.42) | ||||
| Dominant | G/G | 20 (69) | 95 (43.6) | 1 | 0.0096 | 176 | 183 |
| G/A-A/A | 9 (31) | 123 (56.4) | 2.88 (1.25–6.61) | ||||
| Recessive | G/G-G/A | 26 (89.7) | 197 (90.4) | 1 | 0.9 | 182.7 | 189.7 |
| A/A | 3 (10.3) | 21 (9.6) | 0.92 (0.26–3.31) | ||||
| Overdominant | G/G-A/A | 23 (79.3) | 116 (53.2) | 1 | 0.0057 | 175.1 | 182.1 |
| G/A | 6 (20.7) | 102 (46.8) | 3.37 (1.32–8.60) |
OR: Odds ratio
AIC: Akaike information criterion
BIC: Bayesian information criterion