. 2023 Jul 21;18(7):e0277151. doi: 10.1371/journal.pone.0277151

Table 2. Risk factors for CKD of unknown origin in univariable and multivariable logistics regression analysis.

		Univariable model		Multivariable model
		Univariable model		Model 1 ^§		Model 2 ^§§
Variable		OR	95% CI	OR	95% CI	OR	95% CI
Age		1.08	1.07–1.10	1.11	1.09–1.13	1.1	1.09–1.13
Sex	Male	Ref		Ref		Ref
Sex	Female	6.07	4.60–8.01	7.52	5.69–12.77	8.64	5.76–12.98
Marital status	Married	Ref		Ref		Ref
Marital status	Single	3.07	2.11–4.48	1.50	0.93–2.42	1.50	0.93–2.42
Physical activity	1^st Tertile	1.15	0.85–1.55	-		-
	2^nd Tertile	1.49	1.11–2.01	-		-
	3^rd Tertile	Ref		-		-
P for linear trend		0.338		-		-
Low HDL	No	Ref		-		-
Low HDL	Yes	1.17	0.92–1.49	-		-
Hyper TG	No	Ref		Ref		Ref
Hyper TG	Yes	1.72	1.33–2.24	1.53	1.11–2.12	1.55	1.12–2.15
BMI	<18.5	0.26	0.13–0.54	0.32	0.14–0.72	0.32	0.14–0.73
	18.5–25	Ref		Ref		Ref
	> = 25	1.98	1.53–2.58	1.33	0.96–1.84	1.32	0.95–1.84
P for linear trend		<0.001		<0.001		<0.001
Smoking status	Non smoker	Ref		Ref		Ref
	Current smoker	0.32	0.18–0.54	1.04	0.53–2.05	1.05	0.53–2.07
	Previous smoker	0.32	0.21–0.49	0.97	0.55–1.70	1.00	0.57–1.74
Indoor use of pesticides	No	Ref		Ref		-
Indoor use of pesticides	Yes	1.47	1.15–1.87	1.36	1.01–1.84	-
Duration of exposure to indoor pesticides (minutes)	Non users	Ref		-		Ref
	1^st Tertile (<9)	1.56	1.10–2.21	-		1.33	0.87–2.03
	2^ndTertile (9–20)	1.26	0.89–1.80	-		1.16	0.75–1.79
	3^rdTertile (>20)	1.60	1.12–2.28	-		1.64	1.07–2.51
P for linear trend		0.038				0.056

^§ Model 1 included variables: age, sex, marital status, BMI, smoking, TG, house use of pesticides

^§§ Model 2 included variables: age, sex, marital status, BMI, smoking, TG, house use of pesticides exposure time