Table 2. Individual cytokine comparison in the retina between 12-month-old C57Bl6 mice exposed to 670nm light for 1 week compared to age matched controls, represented in Fig 2.
| Target | P-Value | Significance | % Difference |
|---|---|---|---|
| C5a | 0.0076 | ** | 89 |
| IL-16 | 0.0043 | ** | 75 |
| CXCL12 | 0.0022 | ** | 68 |
| M-CSF | 0.0043 | ** | 64 |
| IL-17 | 0.0206 | * | 60 |
| IL-27 | 0.0206 | * | 60 |
| CXCL11 | 0.0076 | ** | 57 |
| TIMP-1 | 0.0022 | ** | 57 |
| IL-2 | 0.0206 | * | 56 |
| IL-13 | 0.0325 | * | 55 |
| IL-23 | 0.013 | * | 49 |
| IL-1ra | 0.0076 | ** | 47 |
| CXCL10 | 0.0898 | ns | 43 |
| IL-4 | 0.119 | ns | 42 |
| IFN-γ | 0.0465 | * | 39 |
| IL-7 | 0.0898 | ns | 38 |
| CXCL9 | 0.026 | * | 37 |
| CCL2 | 0.066 | ns | -33 |
| CCL1 | 0.1937 | ns | 30 |
| TREM-1 | 0.1937 | ns | -29 |
| CD54 | 0.0043 | ** | 27 |
| CXCL13 | >0.9999 | ns | 27 |
| IL-12 p70 | 0.237 | ns | 26 |
| IL-3 | 0.237 | ns | 23 |
| GM-CSF | 0.237 | ns | 18 |
| CCL17 | 0.3939 | ns | 17 |
| TNF-α | 0.3939 | ns | -15 |
| IL-1β | 0.4491 | ns | -15 |
| CXCL2 | 0.3377 | ns | 13 |
| CCL12 | 0.2857 | ns | 13 |
| CXCL1 | 0.3377 | ns | -13 |
| IL-1α | 0.3939 | ns | -10 |
| IL-10 | 0.4491 | ns | -8 |
| G-CSF | >0.9999 | ns | 4 |
| CCL4 | 0.4491 | ns | 3 |
| CCL5 | 0.4491 | ns | 2 |
| CCL11 | >0.9999 | ns | 2 |
| CCL3 | >0.9999 | ns | 1 |
| IL-5 | 0.4491 | ns | 1 |
| IL-6 | 0.4491 | ns | 0 |
The final column represents a heat map of the relative percentage increase or decrease values in expression of each cytokine with red indicating a relatively large change and green a relatively small change. Mann-Whitney U statistical test
*p≤0.05
**p≤0.01, ns = non-significant.