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. 2023 Jul 21;18(7):e0286271. doi: 10.1371/journal.pone.0286271

Fig 7. hbxA regulates the production of nidulanins in A. nidulans.

Fig 7

Wild-type (WT), deletion (ΔhbxA), complementation (hbxA-com) and overexpression (OEhbxA) strains were top-agar inoculated on solid glucose minimum medium (GMM) at 37°C for 72 h. Samples were collected, extracted with chloroform and analyzed by LC-HRMS in positive mode (A-C) Quantification of nidulanin A (m/z 604.34943), B (m/z 620.34404), D (m/z 536.28659) respectively. (D) Heat map of TPM values of nidulanin cluster (DEGs) expression in A. nidulans ΔhbxA and OEhbxA with respect to wild type strain on a log scale found in Inglis et al. [50]. The TPM value of each gene was calculated by averaging all the TPM values of all replicates.