Table 1. Overview of the reports from clinical NR trials included in this review.
| First author | Year published | Group treated | Treatment group size | Placebo group size | Daily NR dose (mg) | Duration | Reference in review |
|---|---|---|---|---|---|---|---|
| Trammell | 2016 | Healthy | 12 | 0 | 100, 300, 1000 | 24 hours | (24) |
| Airhart | 2017 | Healthy | 8 | 0 | 2000 | 8 days | (25) |
| Dellinger | 2017 | Elderly | 40 | 40 | 250, 500 | 60 days | (40) |
| Dollerup | 2018 | Obese, insulin resistant | 20 | 20 | 2000 | 12 weeks | (4) |
| Martens | 2018 | Elderly | 24 | 24 | 1000 | 6 weeks | (37) |
| Conze | 2019 | Healthy | 32–34 | 34 | 100, 300, 1000 | 8 weeks | (32) |
| Dollerup | 2019 | Obese, insulin resistant | 20 | 20 | 2000 | 12 weeks | (5) |
| Elhassan | 2019 | Elderly | 12 | 12 | 1000 | 21 days | (33) |
| de la Rubia | 2019 | Amyotrophic lateral sclerosis | 10–14 | 10–13 | 1000* | 4 months | (43) |
| Zhou | 2020 | Heart failure | 4 | 0 | 2000 | 9 days | (26) |
| Dollerup | 2020 | Obese, insulin resistant | 20 | 20 | 2000 | 12 weeks | (6) |
| Remie | 2020 | Obese | 13 | 13 | 1000 | 6 weeks | (34) |
| Dolopikou | 2020 | Young/elderly | 12 | 12 | 500 | 2 hours | (36) |
| Simic | 2020 | Acute kidney injury | 3–5 | 0–2 | 250, 500, 1000, 2000 | 2 days | (42) |
| Veenhuis | 2021 | Ataxia telangiectasia | 24 | 0 | 25/kg (max 900) | 4 months | (27) |
| Stocks | 2021 | Healthy | 8 | 8 | 1000 | 7 days | (35) |
| Nascimento | 2021 | Obese | 8 | 8 | 1000 | 6 weeks | (39) |
| Wang | 2022 | Heart failure | 20 | 10 | 2000 | 12 weeks | (29) |
| Brakedal | 2022 | Parkinson’s disease | 15 | 15 | 1000 | 30 days | (30) |
| Wu | 2022 | Healthy | 12 | 9 | 1000 | 7 days | (31) |
| Vreones | 2022 | Elderly | 24 | 24 | 1000 | 6 weeks | (38) |
| Dellinger | 2022 | Nonalcholic fatty liver disease | 24–36 | 27–31 | 250, 500 | 6 months | (41) |
| Jensen | 2022 | Elderly | 16 | 15 | 1000 | 44 days | (8) |
| Lapatto | 2023 | Obese | 3–16 | 0 | 1000 | 5 months | (28) |
| Peluso | 2023 | Obese, insulin resistant | 20 | 20 | 2000 | 12 weeks | (7) |
*Not formally disclosed.