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. 2023 Jul 21;9(29):eadh0102. doi: 10.1126/sciadv.adh0102

Fig. 5. BCAS up-regulates astrocyte-related genes in WT but not TRPA1-KO mice.

Fig. 5.

(A) A schematic of RNA-seq in the corpus callosum. (B) A volcano plot comparing all genes in the dataset between BCAS-operated WT and TRPA1-KO mice (average of days 7, 10, and 14). Red dots, reactive astrocyte marker genes. (C) The top 10 astrocyte-related terms in the GO enrichment analysis for differentially expressed genes between BCAS-operated WT and TRPA1-KO mice (average of days 7, 10, and 14). (D) A heatmap of the expression of genes contained in the top three astrocyte-related GO terms (GO:0014002, GO:0043615, and GO:0048708) in the sham-operated group (average of sham-operated WT and TRPA1-KO mice) and in BCAS-operated WT and TRPA1-KO mice (average of days 7, 10, and 14). n = 1.