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. 2023 Jul 7;14:1179534. doi: 10.3389/fmicb.2023.1179534

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Copyright © 2023 Tanaka, Tanigawa, Song, Komatsu, Kuriki, Tanaka, Fukudo, Urano and Fukuda.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparison of enzyme activity between healthy and IBS-n fecal samples. The bar shows the fold change of normalized fluorescence intensity (IBS-n/healthy). These values were sorted by fold change, and the smallest normalized fluorescence intensity value except for 0 was added to all samples as pseudo intensity to calculate the fold change. The color shows the C-terminus of the probes: red for K and R, blue for S and G, and black for other probes. The alphabets represent amino acid residues. Ac = acetyl. For enzyme abbreviations, please refer to Supplementary Figure S1.