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. 2023 Jul 21;56:e12636. doi: 10.1590/1414-431X2023e12636

Table 4. Indirect immunofluorescence-antineutrophil cytoplasmic antibodies (IIF-ANCA) results and diseases before and after technique improvements.

Diseases Standard technique Improved technique
Positivity C-ANCA P-ANCA A-ANCA Positivity C-ANCA P-ANCA A-ANCA
GPA 8/18 (44.4%) 6 (75.0%) 2 (25.0%) 0 9/18 (50.0%) 6 (66.7%) 3 (33.3%) 0
MPA 0 0 0 0 1/6 (16.7%) 1 (100.0%) 0 0
EGPA 0 0 0 0 1/5 (20.0%) 1 (100.0%) 0 0
RLV 0 0 0 0 0 0 0 0
Type 1 AIH 0 0 0 0 3/12 (25.0%) 2 (66.7%) 0 1 (33.3%)
UC 1/19 (5.3%) 0 1 (100.0%) 0 7/19 (36.8%) 4 (57.1%) 1 (14.3%) 2 (28.6%)

AIH: autoimmune hepatitis; EGPA: eosinophilic granulomatosis with polyangiitis; GPA: granulomatosis with polyangiitis; MPA: microscopic polyangiitis; RVL: renal limited vasculitis; UC: ulcerative colitis.