Table 4. Indirect immunofluorescence-antineutrophil cytoplasmic antibodies (IIF-ANCA) results and diseases before and after technique improvements.
Diseases | Standard technique | Improved technique | ||||||
---|---|---|---|---|---|---|---|---|
Positivity | C-ANCA | P-ANCA | A-ANCA | Positivity | C-ANCA | P-ANCA | A-ANCA | |
GPA | 8/18 (44.4%) | 6 (75.0%) | 2 (25.0%) | 0 | 9/18 (50.0%) | 6 (66.7%) | 3 (33.3%) | 0 |
MPA | 0 | 0 | 0 | 0 | 1/6 (16.7%) | 1 (100.0%) | 0 | 0 |
EGPA | 0 | 0 | 0 | 0 | 1/5 (20.0%) | 1 (100.0%) | 0 | 0 |
RLV | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Type 1 AIH | 0 | 0 | 0 | 0 | 3/12 (25.0%) | 2 (66.7%) | 0 | 1 (33.3%) |
UC | 1/19 (5.3%) | 0 | 1 (100.0%) | 0 | 7/19 (36.8%) | 4 (57.1%) | 1 (14.3%) | 2 (28.6%) |
AIH: autoimmune hepatitis; EGPA: eosinophilic granulomatosis with polyangiitis; GPA: granulomatosis with polyangiitis; MPA: microscopic polyangiitis; RVL: renal limited vasculitis; UC: ulcerative colitis.