Figure 3. LMP1 targeting by sequence-specific shRNA inhibited nasopharyngeal carcinoma (NPC)-LMP1 cell growth and migration. A, Cell growth curve showing the proliferation of TW03-LMP1 cells after the treatment of shcontrol, LMP1-shRNA1, and LMP1-shRNA2, according to MTT cell proliferation assay. Statistical analysis was done with data from at least three independent experiments. B, Wound healing assays of TW03-LMP1-shcontrol, TW03-LMP1-shRNA1, and TW03-LMP1-shRNA2 cells. Wound closures were photographed at 0, 12, and 24 h after removing the scratched cells. C, Migration rates were calculated with data from at least three independent experiments. Data are reported as means±SD. **P<0.01, ***P<0.001 (Student's t-test).
