Table 1.
Baseline characteristics at LT among first vs prior decompensation groups
| Factor | First decompensation n = 210 (100%) | Prior decompensation N = 31 (100%) | P value |
|---|---|---|---|
| Agea | 43 (35, 52) | 38 (36, 47) | 0.23 |
| Male | 143 (68) | 16 (52) | 0.07 |
| Race | |||
| White | 177 (85) | 27 (87) | 0.97 |
| African American | 13 (6) | 2 (6) | |
| Latinx | 8 (4) | 1 (3) | |
| Asian | 8 (4) | 1 (3) | |
| Other | 3 (1) | 0 (0) | |
| Insurance | |||
| Private | 138 (66) | 22 (71) | 0.73 |
| Medicare | 14 (7) | 1 (3) | |
| Medicaid | 56 (27) | 8 (26) | |
| Body mass indexa | 29 (25–34) | 31 (25–38) | 0.16 |
| Sodiuma | 136 (133, 140) | 138 (134, 141) | 0.42 |
| INRa | 2.2 (1.9, 2.8) | 2.4 (2.1, 2.9) | 0.35 |
| Bilirubina | 26 (16, 35) | 26 (19, 34) | 0.78 |
| Creatininea | 2.3 (1.4, 3.9) | 1.7 (1.5, 2.8) | 0.28 |
| Renalreplacement therapy | 121 (58) | 20 (67) | 0.35 |
| MELD-Na Scorea | 39 (35, 40) | 39 (36, 40) | 0.98 |
| On ventilator | 33 (17) | 9 (30) | 0.08 |
| Overt hepatic encephalopathy | 100 (50) | 13 (43) | 0.46 |
| Days of abstinencea | 45 (25, 73) | 52 (25, 109) | 0.09 |
| Married or significant other | 134 (64) | 23 (74) | 0.51 |
| History of psychiatric disease | 99 (47) | 17 (57) | 0.33 |
| Current smoker | 42 (21) | 9 (31) | 0.23 |
| Current marijuana | 18 (9) | 4 (13) | 0.47 |
| History of illicit drug use | 28 (14) | 5 (17) | 0.65 |
| History of failed rehab attempts | |||
| No priors | 146 (71) | 16 (53) | <0.001 |
| 1 prior | 47 (23) | 6 (20) | |
| Multiple | 12 (6) | 8 (27) | |
| Family history of alcohol use disorder | |||
| None | 113 (56) | 13 (46) | 0.51 |
| Extended family | 24 (12) | 3 (11) | |
| Immediate family | 64 (32) | 12 (43) | |
| Employment immediately before presentation | 114 (54) | 13 (42) | 0.20 |
| Legal history (e.g., DUI and custody loss because of alcohol) | |||
| None | 167 (80) | 22 (73) | 0.21 |
| 1 prior | 26 (12) | 3 (10) | |
| Multiple | 15 (7) | 5 (17) | |
| Alcoholunits perdaya | 12 (7, 18) | 9 (6, 14) | 0.03 |
| Years of heavy drinking | 12 (6, 20) | 11 (7, 20) | 0.79 |
| Meets NIAAA criteria for AH | 174 (83) | 26 (87) | 0.60 |
| Follow-up time in yearsa | 2.3 (1.1, 4.0) | 1.7 (0.6, 2.9) | 0.08 |
AH, alcohol-associated hepatitis; INR, international normalized ratio; IQR, interquartile range; MELD-Na, Model for End-Stage Liver Disease-Sodium score; NIAAA, National Institute on Alcohol Abuse and Alcoholism.
a
Median (IQR).