Table 5.

Univariable and multivariable analysis for harmful alcohol use following LT hospital discharge

Factor	Univariable HR (95% CI)	P value	Multivariable aHR (95% CI)	P value
Prior decompensation	1.84 (1.01–3.33)	0.05	1.77 (1.07–2.94)	0.03
Age, per year	0.99 (0.96–1.01)	0.30	—	—
Male	0.89 (0.59–1.36)	0.59	—	—
Non-White race/ethnicity	1.57 (0.59–4.17)	0.37	—	—
Private insurance	0.80 (0.49–1.31)	0.38
Body mass index	1.01 (0.94–1.08)	0.75	—	—
Renalreplacement therapy	0.92 (0.63–1.34)	0.66	—	—
MELD-Na	0.94 (0.87–1.01)	0.11	—	—
On ventilator	1.85 (1.30–2.62)	0.001	—	—
Overt hepatic encephalopathy	1.32 (0.77–2.26)	0.32	—	—
Days of abstinence	1.00 (0.99–1.01)	0.78	—	—
Married or significant other	1.25 (0.71–2.21)	0.04	—	—
History of psychiatric disease	1.68 (0.91–3.11)	0.10	—	—
On medications for psychiatric disease	1.50 (1.01–2.23)	0.05	—	—
Current smoker	0.71 (0.26–1.88)	0.48	—	—
Current marijuana	1.15 (0.54–2.44)	0.71	—	—
History of illicit drug use	0.58 (0.24–1.42)	0.23	—	—
History of failed rehab attempts
1 only (vs none)	2.06 (1.36–3.13)	0.001	1.77 (1.07–2.92)	0.02
≥2 (vs none)	3.82 (2.27–6.42)	<0.001	3.54 (2.52–4.95)	<0.001
Family history of alcoholuse disorder
Immediate family (vs none)	0.87 (0.48–1.58)	0.64	—	—
Extended family only	1.18 (0.75–1.84)	0.48	—	—
Employment immediately before presentation	0.86 (0.51–1.44)	0.56	—	—
Any legal history (e.g., DUI and custody loss because of alcohol)	1.90 (1.14–3.17)	0.01	—	—
>10 alcoholunits per day	2.41 (1.52–3.82)	<0.001	2.18 (1.44–3.29)	<0.001
>15 years of heavy drinking	1.08 (0.54–2.19)	0.82	—	—

DUI, driving under the influence; HR, hazard ratio; LT, liver transplantation; MELD-Na, Model for End-Stage Liver Disease-Sodium score..