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. Author manuscript; available in PMC: 2023 Jul 21.
Published in final edited form as: J Alzheimers Dis. 2022;89(2):411–414. doi: 10.3233/JAD-220717

Table 1.

Characteristics of older adults (age ≥65 y) with versus without COVID-19 before and after propensity-score matching

Before matching After matching
COVID-19
Cohort
Non-COVID-19
Cohort
SMD COVID-19
Cohort
Non-COVID-19
Cohort
SMD
Total number 410,748 5,834,534 410,478 410,478
Age (y, mean ± SD) 73.7 ± 7.75 73.0 ± 7.34 0.10* 73.7 ± 7.75 73.7 ± 7.75 <0.001
Sex (%)
 Female 53.6 55.6 0.04 53.6 53.6 <0.001
 Male 46.6 44.4 0.04 46.6 46.6 <0.001
Ethnicity (%)
 Hispanic 6.7 3.5 0.15* 6.7 6.7 <0.001
 Not Hispanic 68.9 63.5 0.11* 68.9 68.9 <0.001
 Unknown 24.4 33.0 0.19* 24.4 24.4 <0.001
Race (%)
 Asian 1.6 1.7 0.002 1.6 1.6 0.001
 Black 10.0 7.8 0.08 10.0 10.0 <0.001
 White 75.3 74.1 0.03 75.3 75.4 <0.001
 Unknown 12.5 16.0 0.10 12.5 12.5 <0.001
Adverse socioeconomic and psychosocial circumstances (%) 13.2 2.9 0.39* 13.2 13.2 <0.001
Comorbidities
 Hypertension 59.4 44.5 0.30* 59.4 59.4 <0.001
 Overweight and obesity 23.0 14.4 0.22* 23.0 23.1 <0.001
 Type 2 diabetes 30.4 17.9 0.29* 30.4 30.4 <0.001
 Depression 22.1 11.5 0.29* 22.1 22.2 <0.001
 Hearing loss 5.9 4.9 0.04 5.9 5.8 0.002
 Traumatic brain injury 3.3 1.5 0.12* 3.3 3.1 0.007
 Tobacco smoking 10.6 7.5 0.11* 10.6 10.6 <0.001
 Heavy alcohol drinking 3.8 2.2 0.10* 3.8 3.8 0.003

COVID-19 cohort—contracted COVID-19 between 2/2020–5/2021. Non-COVID-19 cohort—had no documented COVID-19 but had medical encounters with healthcare organizations between 2/2020–5/2021. Self-identified race and ethnicity as recorded in the TriNetX electronic health records database were included because they have been associated with both infection risk and severe outcomes of COVID-19. SMD, standardized mean differences.

*

SMD greater than 0.1, a threshold being recommended for declaring imbalance.