Skip to main content
. 2023 Jul 6;14:1224892. doi: 10.3389/fimmu.2023.1224892

Table 1.

The inhibitors of AP-1.

Inhibitor Target Strategies Application Reference
T-5224 c-Fos/AP-1 Inhibition of protein-DNA binding Arthritis (72)
SP600125 JNK1/2 Inhibition of AP-1 activation Atherosclerosis (75, 84)
Doxycycline JNK1/2 Inhibition of AP-1 activation Atherosclerosis (77, 85)
MLN944 (XR5944) c-Jun/AP-1 Inhibition of protein-DNA binding Cancers (71, 79)
SR11302 Fra-1/AP-1 Inhibition of protein-DNA binding Head and neck squamous cell carcinoma (80)
SPC839 AP-1/NF-κB Inhibition of transcriptional activity AML (81)
(+)-Glaucarubinone AP-1 Inhibition of AP-1 transcription (83)