Table 1.
Inhibitor | Target | Strategies | Application | Reference |
---|---|---|---|---|
T-5224 | c-Fos/AP-1 | Inhibition of protein-DNA binding | Arthritis | (72) |
SP600125 | JNK1/2 | Inhibition of AP-1 activation | Atherosclerosis | (75, 84) |
Doxycycline | JNK1/2 | Inhibition of AP-1 activation | Atherosclerosis | (77, 85) |
MLN944 (XR5944) | c-Jun/AP-1 | Inhibition of protein-DNA binding | Cancers | (71, 79) |
SR11302 | Fra-1/AP-1 | Inhibition of protein-DNA binding | Head and neck squamous cell carcinoma | (80) |
SPC839 | AP-1/NF-κB | Inhibition of transcriptional activity | AML | (81) |
(+)-Glaucarubinone | AP-1 | Inhibition of AP-1 transcription | (83) |