Table 1.
The inhibitors of AP-1.
| Inhibitor | Target | Strategies | Application | Reference |
|---|---|---|---|---|
| T-5224 | c-Fos/AP-1 | Inhibition of protein-DNA binding | Arthritis | (72) |
| SP600125 | JNK1/2 | Inhibition of AP-1 activation | Atherosclerosis | (75, 84) |
| Doxycycline | JNK1/2 | Inhibition of AP-1 activation | Atherosclerosis | (77, 85) |
| MLN944 (XR5944) | c-Jun/AP-1 | Inhibition of protein-DNA binding | Cancers | (71, 79) |
| SR11302 | Fra-1/AP-1 | Inhibition of protein-DNA binding | Head and neck squamous cell carcinoma | (80) |
| SPC839 | AP-1/NF-κB | Inhibition of transcriptional activity | AML | (81) |
| (+)-Glaucarubinone | AP-1 | Inhibition of AP-1 transcription | (83) |