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. Author manuscript; available in PMC: 2023 Jul 21.
Published in final edited form as: Nat Mach Intell. 2022 Nov 15;4(11):1017–1028. doi: 10.1038/s42256-022-00561-w

Fig. 3 |. Evaluating gMVP and published methods in identifying damaging variants in known disease genes such as TP53, PTEN, BRCA1 and MSH2.

Fig. 3 |

The precision–recall curves of gMVP and published methods are shown for each gene using functional readout data—labelled on the basis of the recommended threshold—as the ground truth.