Fig. 2 |. Influence of platelet sGC on leukocyte adhesion in vitro.

a,b, WT monocyte (a) and neutrophil (b) adhesion to WT ECs after incubation with supernatant of activated platelets isolated from either Pf4-Cre+Gucy1b1LoxP/LoxP or Pf4-Cre+Gucy1b1+/LoxP mice. Each symbol represents 1 independent animal (n = 8 per group). Two-sided unpaired t-test. Data are the mean ± s.e.m. c, Quantification of neutrophil adhesion after preincubation of either ECs or neutrophils with supernatant of activated platelets from Pf4-Cre+Gucy1b1LoxP/LoxP mice in comparison to non-preincubation conditions. Each symbol represents 1 paired sample (each derived from n = 8 independent animals). Repeated measures one-way ANOVA with Tukey test for multiple testing. Data are the mean ± s.e.m.