Skip to main content
. Author manuscript; available in PMC: 2023 Jul 21.
Published in final edited form as: Nat Cardiovasc Res. 2022 Dec 12;1(12):1174–1186. doi: 10.1038/s44161-022-00175-w

Extended Data Fig. 2 |. Platelet aggregation in control and platelet sGC knockout (Pf4-Cre+Gucy1b1LoxP/LoxP) mice.

Extended Data Fig. 2 |

Platelet aggregation in control and platelet sGC knockout (Pf4-Cre+Gucy1b1LoxP/LoxP) mice after stimulation with adenosine diphosphate (ADP, a) the platelet-activated receptor 4 agonist PAR4-AP (b), the thromboxane analog U46619 (c), and collagen (d). Each experiment was performed in the presence of DMSO (vehicle) or the nitric oxide donor sodium nitroprusside (SNP). Each symbol represents one independent animal (n = 6). Aggregation tracings represent the mean values of investigated animals per genotype. Two-sided unpaired t-test (except A, vehicle and D, vehicle: two-sided Mann-Whitney U-test). Data are mean and s.e.m.