Figure 7. Increase in relative peripherin-2 level produces long incisures of varying shape.
(A–C) Representative TEM images of tangentially sectioned Rho+/- mouse retinas. Incisures can be relatively straight and extend nearly the entire disc diameter (A) or be bifurcated or twisted (B). In some cells, incisures are associated with tubular structures (C). (D) Representative TEM image of a tangentially sectioned Rho-/- retina. While lacking discs, the outer segment cilium contains a large number of tubular structures. Yellow arrowheads point to incisure ends; orange arrows point to tubular structures. Scale bar: +/- µm.