Table 2. Summary of quantitative parameters determined for mouse discs.
Calculated parameter | WT | Rho+/- |
---|---|---|
Disc surface area (both lamellae) | 3.53 µm2 | 1.80 µm2 |
Rhodopsin molecules per disc | 75,000 | 38,200 |
Peripherin-2+ROM1 molecules per disc | 5,910 | 6,360 |
Total rim length | 6.21 µm | N/A* |
Measured incisure length as % of disc diameter | 50%† | N/A* |
Theoretical incisure length as % of disc diameter | - | 155% |
Incisure and total rim lengths in Rho +/- discs cannot be readily measured due to incisure complexity.
The value is taken from the measurements shown in Figure 6.