Table 1.
The demographic information, Child-Pugh grade and laboratory indication of LC and HC.
| Indicator | Normal range | LC | HC | P (LC vs. HC) | P (CPC vs. DCPC) | ||
|---|---|---|---|---|---|---|---|
| CPC | DCPC | ||||||
| Demographic indicators | Male(%) | 17(60.7%) | 9(56%) | 0.77 | / | ||
| 5(62.5%) | 12(60%) | / | 0.952 | ||||
| Age | 54.79 ± 12.68 | 54.25 ± 10.14 | 0.89 | / | |||
| 49.00 ± 12.84 | 57.10 ± 12.17 | / | 0.257 | ||||
| Child-Pugh grade | Child-Pugh A | 7 | 13 | ||||
| Child-Pugh B | 0 | 6 | / | / | / | ||
| Child-Pugh C | 1 | 1 | |||||
| Laboratory indicator | WBC(*10^9/L) | 3.5-9.5 | 5.53 ± 1.23 | 3.29 ± 1.23* | 5.20 ± 1.26 | 0.009 | <0.001 |
| N(*10^9/L) | 1.8-6.3 | 3.59(2.78,4.58) | 1.68(1.35,2.41) * | 3.07 ± 0.86 | 0.106 | 0.001 | |
| N% | 40.0-75.0 | 70.00(59.90,73.15) | 64.95(49.78,72.50) | 59.04 ± 7.17 | 0.075 | 0.309 | |
| Hb(g/L) | 130-175 | 137.25 ± 19.69 | 105.55 ± 26.68* | 128.13 ± 6.23 | 0.022 | 0.005 | |
| PLT(*10^9/L) | 125-350 | 100.50(92.00,161.75) | 60.50(46.50,86.75) * | 179.94 ± 22.86 | <0.001 | 0.004 | |
| ALT(U/L) | 7.0-40.0 | 40.30(22.58,111.93) | 20.30(15.00,50.75) | 19.90 ± 9.32 | 0.045 | 0.170 | |
| AST(U/L) | 13.0-35.0 | 32.85(27.33,92.65) | 30.75(24.38,51.00) | 17.38 ± 4.87 | <0.001 | 0.629 | |
| TBIL(μmmol/l) | 3.4-17.1 | 14.65(8.78,34.10) | 16.30(12.50,24.83) | 8.61 ± 3.21 | <0.001 | 0.593 | |
| DBIL(μmmol/l) | 0-6.0 | 4.85(3.90,13.90) | 6.50(4.83,10.28) | 3.82 ± 1.36 | <0.001 | 0.576 | |
| IBIL(μmmol/l) | 0-11.1 | 10.00(4.58,20.20) | 10.40(8.15,15.20) | 4.79 ± 1.96 | <0.001 | 0.684 | |
| ALB(g/L) | 40.0-55.0 | 39.58 ± 6.76 | 36.69 ± 6.11 | 46.81 ± 3.85 | <0.001 | 0.282 | |
| GLO(g/L) | 20.0-40.0 | 28.68 ± 5.34 | 34.72 ± 7.70 | 32.38 ± 3.38 | 0.218 | 0.054 | |
| TBA(μmmol/l) | 0-10.0 | 29.40(5.38,54.75) | 30.60(13.53,52.43) | 3.80 ± 0.96 | <0.001 | 0.666 | |
| CREA(μmmol/l) | 44.0-133.0 | 72.00(60.05,88.75) | 74.30(53.10,87.35) | 57.13 ± 9.36 | 0.006 | 0.819 | |
| BUN(mmol/L) | 2.90-7.14 | 4.75(3.85,5.78) | 4.82(3.94,7.26) | 4.52 ± 1.00 | 0.241 | 0.576 | |
| Na(mmol/L) | 137.0-147.0 | 140.16 ± 2.80 | 140.47 ± 2.84 | 141.88 ± 2.19 | 0.072 | 0.800 | |
| PT(s) | 10.0-14.0 | 14.75 ± 2.68 | 14.59 ± 1.91 | 11.78 ± 0.80 | <0.001 | 0.856 | |
| PTA(%) | 80.0-120.0 | 86.00(63.43,103.90) | 71.35(68.00,80.10) | 100.06 ± 10.32 | <0.001 | 0.525 | |
| INR | 0.85-1.20 | 1.19 ± 0.25 | 1.23 ± 0.13 | 1.02 ± 0.09 | <0.001 | 0.545 | |
CPC, compensated cirrhosis; DCPC, decompensated cirrhosis; HC, healthy control; WBC, white blood cell count; N, neutrophil count; N%, neutrophil count over white blood cell count; LYM, lymphocyte count; Hb, hemoglobin; PLT, platelet count; ALT, alanine aminotransferase; AST, aspartate aminotransferase; TBIL, total bilirubin; DBIL, direct bilirubin; IBIL, indirect bilirubin; ALB, blood albumin; GLO, globulin; TBA, bile acid; CREA, creatinine; BUN, urea nitrogen; Na, serum sodium ion concentration; PT, prothrombin time; PTA, prothrombin time percentage; INR, international normalized ratio. * For comparison between CPC and DCPC (significant difference between groups, p<0.05).