Table 2.
Associations between the systemic immune-inflammation index and coronary heart disease.
| Variable | Non-adjusted | Adjust I | Adjust II |
|---|---|---|---|
| OR (95% CI) | OR (95% CI) | OR (95% CI) | |
| p-value | p-value | p-value | |
| SII percentile | 0.98 (0.73, 1.33) | 0.66 (0.48, 0.90) | 0.74 (0.40, 1.36) |
| 0.9169 | 0.0086 | 0.3342 | |
| SII (Quartile) | |||
| Q1 | 1.0 (Ref) | 1.0 (Ref) | 1.0 (Ref) |
| Q2 | 0.75 (0.59, 0.96) | 0.72 (0.55, 0.93) | 0.73 (0.53, 1.00) |
| 0.0242 | 0.0136 | 0.0526 | |
| Q3 | 0.90 (0.71, 1.14) | 0.79 (0.62, 1.02) | 0.83 (0.59, 1.16) |
| 0.3641 | 0.0719 | 0.2760 | |
| Q4 | 0.87 (0.69, 1.11) | 0.63 (0.48, 0.81) | 0.61 (0.39, 0.95) |
| 0.2728 | 0.0003 | 0.0292 | |
| p for trend | 0.6215 | 0.0017 | 0.0639 |
The non-adjusted model adjusts for: none. Adjust I model to adjust for: gender (male-female), age (year), and race (Mexican American, other Hispanic, non-Hispanic White, non-Hispanic black, and other race). Adjust II models adjust for Gender (male-female), age (year), race (Mexican American, other Hispanic, non-Hispanic White, non-Hispanic black, and other race), marital status (with or without a partner), educational level (above high school/below high school), smoking (smoker/non-smoker), drinking (drinking less than or more than 15 drinks in past 12 mos), BMI (normal/overweight/obesity), household income-to-poverty ratio (PIR), cholesterol, triglyceride, total protein, albumin, globulin, serum glucose, serum calcium and white blood cell platelet, neutrophil, lymphocyte, monocyte count, Angina and hypertension (Yes/No). SII grouping standard: Q1: <317.5; Q2: 317.5–445.7; Q3: 445.7–625.1; Q4: >625.7.