Table 3.

Subgroup analysis of SII percentile.

SII percentile	N	OR (95% CI)	p-value	p for interaction
Gender				0.1813
Male	8,439	1.27 (0.89,1.80)	0.1916
Female	7,466	0.80 (0.44,1.42)	0.4401
Age				0.5352
<60 years	11,527	0.76 (0.39,1.49)	0.4263
≥60 years	4,378	0.97 (0.69,1.36)	0.8428
BMI				0.3033
Obese	5,993	0.78 (0.50,1.22)	0.2828
Overweight	5,227	0.90 (0.53,1.52)	0.6852
Normal	4,685	1.44 (0.76,2.75)	0.2627
Race				0.423
Mexican American	2,252	0.47 (0.14,1.61)	0.2284
Other Hispanic	1,592	0.96 (0.33,2.82)	0.9444
Non-Hispanic white	6,892	0.93 (0.63,1.37)	0.7114
Non-Hispanic black	3,235	0.45 (0.19,1.07)	0.0703
Other race	1,934	0.48 (0.14,1.58)	0.2244
Education level				0.7390
Below high school	2,898	1.09 (0.56,2.10)	0.8021
Above high school	13,007	0.96 (0.68,1.35)	0.8096
Marital status				0.2961
Without partner	6,434	1.21 (0.74,1.97)	0.4406
With partner	9,471	0.87 (0.59,1.28)	0.4786
Smoking				0.6743
Non-smoker	8,352	0.85 (0.51,1.42)	0.5425
Smoker	7,553	0.98 (0.67,1.42)	0.9020
Drinking (past 12 mos)				0.9114
<15	15,782	0.99 (0.73,1.33)	0.9276
≥15	123	0.78 (0.01,45.87)	0.9058
High blood pressure				0.7249
No	10,685	0.95 (0.50,1.78)	0.8677
Yes	5,220	0.83 (0.59,1.17)	0.2935
Angina/angina pectoris				0.9263
No	15,584	0.95 (0.67,1.35)	0.7605
Yes	321	0.98 (0.48,2.03)	0.9639

The results of the subgroup analysis were adjusted for all covariates except the effect modifier. 95% CI, 95% confidence interval; OR, odds ratio; BMI was categorized as normal (<25 kg/m²), overweight (25–29.9 kg/m²), and obese (≥30 kg/m²); SII, systemic immune-inflammation index.