Table 6.

Estimates of lung function in the linear mixed model considering the influence of smoking and monthly exposure time to extreme cold temperatures

Parameter	Intercept at 1st examination (95% CI)	Slope (95% CI)	p	Adjusted slope (95% CI)	p	Adjusted slope* (95% CI)	p	Restricted to first 7 examinations	p
FEV1 (%-pred.)	95.04 (91.63 – 98.46)	0.32 (0.15 to 0.48)	< 0.001	0.32 (0.16 to 0.49)	< 0.001	0.32 (0.15 to 0.49)	< 0.001	0.25 (− 0.18 to 0.68)	0.255
FVC (%-pred.)	97.25 (94.15–100.34)	0.43 (0.28 to 0.58)	< 0.001	0.43 (0.28 to 0.58)	< 0.001	0.41 (0.20 to 0.62)	< 0.001	0.29 (− 0.30 to 0.88)	0.333
FEV1/FVC (%-pred.)	96.95 (95.21–98.69)	− 0.07 (− 0.14 to − 0.00)	0.049	− 0.07 (− 0.13 to 0.00)	0.057	− 0.06 (− 0.15 to 0.03)	0.193	− 0.08 (− 0.32 to 0.17)	0.540
DL,CO (%-pred.)	94.59 (90.32–98.87)	− 0.09 (− 0.40 to 0.22)	0,579	− 0.11 (− 0.42 to 0.21)	0.513	− 0.14 (− 0.56 to 0.28)	0.502	− 0.47 (− 2.12 to 1.19)	0.573
DL,CO/VA (%-pred.)	94.89 (90.83–98.96)	0.29 (− 0.05 to 0.62)	0.090	0.22 (− 0.11 to 0.56)	0.201	0.39 (0.02 to 0.76)	0.038	− 0.68 (− 2.11 to 0.75)	0.347

CI confidence interval, D_L,CO diffusion capacity for CO, D_L,CO/VA Krogh-factor, FEV₁ forced expiratory volume in the first second, FEV₁/FVC Tiffeneau-Index, FVC forced vital capacity, SD standard deviation

All models adjusted for smoking status and monthly exposure (≤ 16 h, > 16 h)

*Adjsuted for smoking status and monthly exposure [h]